Snapshot A 24-year-old woman with a past medical history of vitiligo presents to the emergency room for abdominal pain. She has had abdominal pain intermittently for the past few weeks and has seen her primary care physician for this issue. On exam, she is slightly jaundiced with scleral icterus and has hepatosplenomegaly. Viral serologies are negative. Labs are significant for elevated transaminitis and positive smooth muscle antibody. She is started on prednisone. Introduction Clinical definition login to view 8 more bullets Associated conditions login to view 4 more bullets Epidemiology Demographics login to view 5 more bullets Risk factors login to view 3 more bullets Genetics login to view 1 more bullet ETIOLOGY Pathogenesis login to view 1 more bullet Presentation Symptoms and physical exam login to view 7 more bullets Studies Diagnostic testing login to view 19 more bullets Differential Viral hepatitis login to view 2 more bullets Hemochromatosis login to view 2 more bullets Treatment First-line login to view 7 more bullets Second line login to view 8 more bullets Complications Cirrhosis Hepatocellular carcinoma Prognosis Relapse is common