Review Question - QID 215127

A 28-year-old man presents to the emergency department after a penetrating foot injury. He was working on construction scaffolding when he stepped on a nail. The nail penetrated the sole of his right shoe and heel pad. He denies fever, diaphoresis, or muscle spasms. His medical history consists of type 1 diabetes for which he takes insulin. He completed a full childhood vaccine series and his last tetanus booster was 8 years ago. The patient’s temperature is 98.8°F (37.1°C), blood pressure is 138/78 mmHg, pulse is 92/min, and respirations are 18/min. Physical exam reveals a 1 cm puncture wound over the sole of his right foot. The wound appears approximately 2 cm deep. Dried blood, dirt, and shards of grass are visible on the skin surrounding the wound. A complete neurovascular exam of the right lower extremity is normal. His facial expressions appear normal. Which of the following is the most appropriate prophylactic treatment regimen?