Review Question - QID 214910

A 51-year-old gravida 3 para 3 woman comes to the office with reports of involuntary losses of urine that have been occurring for the past 7 months. She states that her dribbling of urine occurs throughout most of the day and even at night, and she must now wear absorbent pads to work. She denies any dysuria, hematuria, or associated polydipsia. She has a history of anxiety, hypertension, and type 2 diabetes diagnosed 7 years ago. She is poorly compliant with her medications and is unsure of what she has been prescribed in the past. Her temperature is 99.1°F (37.3°C), blood pressure is 135/80 mmHg, pulse is 78/min, and respirations are 14/min. Pelvic exam reveals fullness above the pubic symphysis and absent Achilles tendon reflexes bilaterally. Laboratory studies show:

Hemoglobin A1c: 8.8%

Urine:
Color: Yellow
Appearance: Clear
Specific gravity: 1.010
pH: 6.5
Protein: Trace
Glucose: 2+
Ketone: 1+
Blood: Negative
Nitrite: Negative
Epithelial cells: 1 per hpf
Leukocytes: 0 per hpf
Leukocyte esterase: Negative
Bacteria: None

Besides medical management of her diabetes, which of the following is the most appropriate pharmacotherapy for this patient’s urinary symptoms?