Review Question - QID 214798

A 15-year-old girl presents with a 10-month history of frequent menstruation associated with heavy bleeding. Menarche occurred at age 13. She has had light periods every 28-30 days, lasting 5 days with minimal cramping. Over the past 10 months, she has had 14 periods, all of which have lasted 8-10 days and have caused her to bleed through a regular menstrual pad every 3 hours for the first 4-5 days of each period. Her last menstrual period began 2 weeks ago. She endorses fatigue but does not have bruising, epistaxis, or excessive bleeding with dental work. She does not have significant medical or surgical history and takes no medications. She denies being sexually active. Her temperature is 98.6°F (37.0°C), blood pressure is 104/76 mmHg, pulse is 88/min, and respirations are 16/min. Her BMI is 23 kg/m^2. The patient appears slightly pale. Laboratory values are as follows.

Hemoglobin: 10.5 g/dL
Mean corpuscular volume: 74 um^3
Leukocyte count: 6,000/mm^3 with normal differential
Platelet count: 250,000/mm^3
Peripheral blood smear: Red blood cells (RBCs) of normal morphology, normochromic and microcytic
Ferritin: 9 ng/mL
Prothrombin time: 14 seconds
Partial thromboplastin time (activated): 33 seconds
Urine human chorionic gonadotropin (ß-hCG): Negative
Von Willebrand factor antigen: Normal
Von Willebrand factor activity: Normal

In addition to iron supplementation, which of the following is the most appropriate next step in management for this patient?