Review Question - QID 214724

A 57-year-old man with a past medical history of smoking, alcohol use disorder, type 2 diabetes, and hypertension presents to the emergency department with leg pain. He states it started this morning and has rapidly worsened. The patient does not regularly see a doctor and takes no medications, but has noticed weight loss, diarrhea, and yellowing of his skin recently. His temperature is 99.2°F (37.3°C), blood pressure is 110/65 mmHg, pulse is 72/min, respirations are 16/min, and oxygen saturation is 100% on room air. Physical exam reveals diffuse yellowing of the patient’s skin. His abdomen is nontender and his rectal exam demonstrates no blood. A CT scan demonstrates a mass in the pancreas. Inspection of the patient's lower extremity reveals the finding in Figure A which is tender and swollen compared to the other side. Which of the following is the most likely diagnosis?