Review Question - QID 213674

A 67-year-old man presents to the emergency department for evaluatin of abdominal pain. He states he has had abdominal pain that has been worsening over the last several months. He reports that he notices pain only after eating, and states that the pain is located across his entire abdomen and is difficult to locate. He reports having associated bloody bowel movements on a few occasions. His wife states that this pain has caused him to eat less, and that he has lost ten pounds over the last several weeks. The patient’s past medical history is significant for diabetes, hypertension, hyperlipidemia, and a 30 pack-year smoking history. His temperature is 99.2°F (37.3°C), blood pressure is 150/95 mmHg, pulse is 72/min, respirations are 16/min, and oxygen saturation is 100% on room air. Physical exam is notable for a soft, nontender, non-distended abdomen. He states his pain has mostly resolved. Which of the following best describe the pathophysiology of this patient's condition?