Review Question - QID 213475

A 33-year-old homeless man presents to the emergency department with an altered mental status. The patient was found minimally responsive at a local mall and was brought in by police. The patient has a past medical history of polysubstance abuse, anxiety, depression, and panic disorder. His current medications include sertraline, clonazepam, and amitriptyline. His temperature is 98.7°F (37.1°C), blood pressure is 117/68 mmHg, pulse is 80/min, respirations are 10/min, and oxygen saturation is 98% on room air. Physical exam is notable for a somnolent man. Neurological exam reveals 4 mm pupils, which are equal and reactive to light, and a patient who responds incoherently to questions when stimulated. The patient has normoactive bowel sounds and is non-tender in all 4 quadrants. Laboratory values are ordered as seen below.

Serum:
Na+: 139 mEq/L
Cl-: 100 mEq/L
K+: 4.3 mEq/L
HCO3-: 25 mEq/L
BUN: 20 mg/dL
Glucose: 99 mg/dL
Creatinine: 1.1 mg/dL
Ca2+: 10.2 mg/dL
Ethanol: negative

An initial ECG is unremarkable. Which of the following is the best treatment for this patient?