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Review Question - QID 212872

Evaluating Diagnostic Tests Sensitivity, Specificity, PPV, NPV Sensitivity and specificity are intrinsic to the diagnostic test QID: 212872 (M2.OMB.19.5)
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QID 212872 (Type "212872" in App Search)
A research group has developed a low-cost diagnostic retinal imaging device for cytomegalovirus retinitis in a population of HIV-infected patients. In a pilot study of 50 patients, the imaging test detected the presence of CMV retinitis in 50% of the patients. An ophthalmologist slit lamp examination, which was performed for each patient to serve as the gold standard for diagnosis, confirmed a diagnosis of CMV retinitis in 20 patients that were found to be positive through imaging, as well as 1 patient who tested negative with the device. If the prevalence of CMV retinitis in the population decreases due to increased access to antiretroviral therapy, how will positive predictive value and negative predictive value of the diagnostic test be affected?
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