Review Question - QID 212751

An 18-month-old girl is brought to the pediatrician by her mother for vaginal bleeding. The mother states that she noticed the bleeding today, which appeared as brown discharge with clots in the patient’s diaper. The mother denies frequent nosebleeds or easy bruising. She also denies any known trauma. She does mention that the patient has been limping and complaining of left leg pain since a fall 2 months ago. On physical exam, there are multiple 2-3 cm hyperpigmented patches on the patient’s trunk. There is bilateral enlargement of the breasts but no pubic hair. The vaginal orifice is normal and clear with an intact hymen. A plain radiograph of the left lower leg shows patchy areas of lytic bone and sclerosis within the femoral metaphysis. Which of the following is associated with the patient’s most likely diagnosis?