Review Question - QID 212671

A 33-year-old man presents to his primary care physician for numbness and tingling in his hands. He does not typically see a physician, but states that he has had some worsening numbness and weakness in his hands that has been progressing over the past month. His temperature is 99°F (37.2°C), blood pressure is 120/66 mmHg, pulse is 80/min, respirations are 16/min, and oxygen saturation is 99% on room air. Physical exam is notable for a man with strange facial features including an enlarged mandible. The patient is tall and has very large hands with symptoms of numbness and pain reproduced when tapping over the flexor retinaculum of the wrist. Routine laboratory values demonstrate a fasting blood glucose of 155 mg/dL. Which of the following is the most likely cause of mortality in this patient?