Review Question - QID 212494

A 64-year-old man presents to the clinic complaining of low back pain. He was diagnosed with benign prostatic hypertrophy several years ago, which worsened last year. A hard nodule was felt on a digital rectal exam, which led to a prostate biopsy that revealed high-grade adenocarcinoma. A bone scan at that time showed small, focal abnormalities in the lumbar spine. He subsequently underwent radiation therapy to his prostate and pelvic lymph nodes. He was then placed on leuprolide and an anti-androgen. He was doing well until 2 months ago when he developed low back pain, which has worsened since then. He reports that the pain is 8/10 and nearly constant. He states that the pain not only affects his ability to fall asleep but also wakes him up at night. The pain is mildly alleviated by ibuprofen. In addition to prostate cancer, his medical history is significant for hypertension, hyperlipidemia, recurrent nephrolithiasis, and gastroesophageal reflux disease. He takes aspirin, lisinopril, rosuvastatin, and pantoprazole. Upon physical examination, there is midline tenderness within the lumbar region. Magnetic resonance imaging of the spine is obtained, which shows bony metastasis to the L2 and L3 spine without evidence of fracture or spinal cord compression. His prostate-specific antigen is 17.5 ng/mL. Which of the following is the best next step in management?