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Review Question - QID 210728

Primary Amenorrhea Etiology most cases are due to genetic causes or anatomical abnormalities QID: 210728 (M2.OMB.18.4828)
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QID 210728 (Type "210728" in App Search)
A 17-year-old girl presents to the gynecologist's office due to a lack of menarche. She has been sexually active with 1 male lifetime partner and always uses a condom. Her mother believes that breast development started at 11 years old. Her temperature is 98.6°F (37°C), blood pressure is 110/71 mmHg, pulse is 61/min, and respirations are 12/min. On exam, she is a well-appearing, non-hirsute teenager with Tanner 5 breast and pubic hair development. Her pelvic exam reveals normal external genitalia, a shortened vagina, and the cervix is unable to be visualized. Initial laboratory testing for hormone levels and karyotype is normal, and imaging confirms what you suspect on the exam. What is the most likely cause of her lack of menstruation?
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