Review Question - QID 210396

A 47-year-old woman presents to the clinic with difficulty swallowing that started 1 month ago. The patient has experienced weight loss of 10 lbs during this time, without a change in her appetite. She denies fatigue, cough, hoarseness, pain, or hemoptysis. The patient has a history of childhood lymphoma, which was treated with radiation. She takes no medications. She has smoked 1 pack of cigarettes per day since she was 25 years old. Her temperature is 98.9°F (37.2°C), blood pressure is 127/84 mmHg, pulse is 100/min, respirations are 14/min, and oxygen saturation is 98% on room air. Her physical exam is notable for a palpable nodule on the right side of the thyroid. An ultrasound is performed, which confirms a 1.2 cm hyperechoic nodule in the right lobe. Thyroid function labs are drawn and shown below:

Serum TSH: 0.2 mU/L
Serum thyroxine (T4): 187 nmol/L
Serum triiodothyronine (T3): 3.3 nmol/L

Which of the following is the most appropriate next step in management?