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Review Question - QID 109463

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QID 109463 (Type "109463" in App Search)
A 72-year-old man presents to his primary care physician with progressively worsening hearing loss. He states that his trouble with hearing began approximately 7-8 years ago. He is able to hear when someone is speaking to him; however, he has difficulty with understanding what is being said, especially when there is background noise. In addition to his current symptoms, he reports a steady ringing in both ears, and at times experiences dizziness. Medical history is significant for three prior episodes of acute otitis media. Family history is notable for his father being diagnosed with cholesteatoma. His temperature is 98.6°F (37°C), blood pressure is 138/88 mmHg, pulse is 14/min, and respirations are 13/min. On physical exam, when a tuning fork is placed in the middle of the patient's forehead, sound is appreciated equally on both ears. When a tuning fork is placed by the external auditory canal and subsequently on the mastoid process, air conduction is greater than bone conduction. Which of the following is most likely the cause of this patient's symptoms?

Accumulation of desquamated keratin debri

9%

17/186

Eustachian tube obstruction secondary to nasopharyngeal inflammatory edema

2%

4/186

Stapedial abnormal bone growth

5%

10/186

Cochlear hair cell degeneration

68%

127/186

Endolymphatic hydrops

12%

23/186

Select Answer to see Preferred Response

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This patient's age and progressive bilateral sensorineural hearing loss is suggestive of presbycusis, which can result from degeneration of cochlear hair cells.

Hearing loss can be divided into conductive and sensorineural. Conductive hearing loss describes an impairment in transmitting sound from the external environment into the inner ear. Sensorineural hearing loss describes an impairment in transducing sound into neuronal signals. Therefore, conductive hearing loss results from pathology affecting the outer (e.g., trauma) and middle ear (e.g., cholesteatoma,) and sensorineural hearing results from pathology affecting the inner ear (e.g., presbycusis). Presbycusis appears to be associated with a disorder affecting cochlear structures, such as the stria vascularis, hair cells, and spiral ganglion.

Incorrect Answers:
Answer 1: Accumulation of desquamated keratin debris is suggestive of cholesteatoma, which results in conductive hearing loss.

Answer 2: Eustachian tube obstruction secondary to nasopharyngeal inflammatory edema can be seen in acute otitis media (AOM.) AOM results in a conductive hearing loss. Also, the absence of fever, otalgia, and upper respiratory symptoms makes AOM less likely.

Answer 3: Stapedial abnormal bone growth can be seen in otosclerosis, which results in a conductive hearing loss.

Answer 5: Endolymphatic hydrops can be seen in Meniere's disease, which results in sensorineural hearing loss. Typically, the sensorineural hearing loss is unilateral. Patient's with this disease classically present with a sense of ear fullness and/or ipsilateral tinnitus, vertigo, and hearing loss. These clinical findings are usually observed during attacks.

Bullet Summary:
Presbycusis results in bilateral sensorineural hearing loss that can result from cochclear hair cell degeneration.

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