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Review Question - QID 109217

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QID 109217 (Type "109217" in App Search)
A 54-year-old male presents to the emergency department with nasal congestion and sore throat. He also endorses ten days of fatigue, rhinorrhea and cough, which he reports are getting worse. For the last four days, he has also had facial pain and thicker nasal drainage. The patient’s past medical history includes obesity, type II diabetes mellitus, and mild intermittent asthma. His home medications include metformin and an albuterol inhaler as needed. The patient has a 40 pack-year smoking history and drinks 6-12 beers per week. His temperature is 102.8°F (39.3°C), blood pressure is 145/96 mmHg, pulse is 105/min, and respirations are 16/min. On physical exam, he has poor dentition. Purulent mucus is draining from his nares, and his oropharynx is erythematous. His maxillary sinuses are tender to palpation.

Which one of the following is the most common risk factor for this condition?

Asthma

10%

4/42

Diabetes mellitus

12%

5/42

Poor dentition

10%

4/42

Tobacco use

24%

10/42

Viral infection

43%

18/42

Select Answer to see Preferred Response

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This patient presents with fever, purulent nasal discharge, tenderness of the maxillary sinuses (with likely gram-positive diplococci on gram stain), which suggests a diagnosis of acute bacterial rhinosinusitis (ABRS). Viral upper respiratory infection is the most common predisposing risk-factor for ABRS.

ABRS presents with fever, headache, nasal congestion, purulent nasal drainage, sore throat, and cough. It is most commonly caused by Streptococcus pneumonia, Haemophilus influenzae, and Moraxella catarrhalis, and the most common risk factor is a viral upper respiratory infection due to the mucosal inflammation and disruption of the mucociliary elevator. The treatment of choice is amoxicillin-clavulanic acid.

Incorrect Answers:
Answer 1: Asthma can be exacerbated by either acute viral or bacterial rhinosinusitis, but it is not itself a risk factor for development of acute bacterial rhinosinusitis.

Answer 2: Diabetes mellitus is a risk factor for invasive fungal rhinosinusitis, which is a possible diagnosis, but is not more likely than bacterial sinusitis. Fungal rhinosinusitis also classically presents with necrotic areas in the nares or oral cavity and cranial nerve involvement. Purulent nasal drainage is less common.

Answer 3: Poor dentition is a risk factor for odontogenic infections, which may lead to infections of the deep fascial spaces of the head and neck, and Ludwig's angina. It is not known to be a risk factor for acute bacterial rhinosinusitis.

Answer 4: Tobacco use predisposes to acute bacterial rhinosinusitis by causing mucosal irritation, but it is a less common predisposing risk-factor than viral upper respiratory infection.

Bullet Summary:
Viral upper respiratory infection is the most common predisposing risk-factor for acute bacterial rhinosinusitis due to disruption of the mucociliary elevator.

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