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Review Question - QID 109114

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QID 109114 (Type "109114" in App Search)
A 28-year-old man presents to his primary care physician after experiencing intense nausea and vomiting yesterday. He states that he ran a 15-kilometer race in the morning and felt well while resting in a hammock afterward. However, when he rose from the hammock, he experienced two episodes of emesis accompanied by a sensation that the world was spinning around him. This lasted about one minute and self-resolved. He denies tinnitus or hearing changes, but he notes that he still feels slightly imbalanced. He has a past medical history of migraines, but he typically does not have nausea or vomiting with the headaches. At this visit, the patient’s temperature is 98.5°F (36.9°C), blood pressure is 126/81 mmHg, pulse is 75/min, and respirations are 13/min. Cardiopulmonary exam is unremarkable. Cranial nerves are intact, and gross motor function and sensation are within normal limits. When the patient’s head is turned to the right side and he is lowered quickly to the supine position, he claims that he feels “dizzy and nauseous.” Nystagmus is noted in both eyes. Which of the following is the best treatment for this patient’s condition?

Particle repositioning maneuver

86%

30/35

Thiazide diuretic

0%

0/35

Triptan therapy

3%

1/35

Meclizine

9%

3/35

Increased fluid intake

3%

1/35

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This patient had a brief episode of vertigo, nausea, and vomiting and exhibits a positive Dix-Hallpike test, which is most consistent with benign positional vertigo (BPV). The best treatment is the Epley maneuver, which repositions particles in the inner ear.

BPV presents with sudden movement followed by intense vertigo, nausea, and vomiting. The episodes typically last less than one minute, but feeling imbalanced afterward is commonplace. The Dix-Hallpike test is the principle method of diagnosing BPV. The Epley maneuver repositions the free-floating calcium particles, which are felt to be the source of the symptoms, from the semicircular canal into the utricle and is the first-line treatment.

Incorrect Answers:
Answer 2: A thiazide diuretic would be appropriate for Meniere’s disease, which presents with vertigo, tinnitus, and hearing loss with a feeling of fullness in the ear. The medication works to reduce endolymph build-up in the inner ear.

Answer 3: Triptan therapy is an abortive treatment for migraine headaches and acts through agonist activity at the serotonin 5HT-1B and -1D receptors. Although migraines can cause vertigo, nausea, and vomiting, and this patient does have a history of migraines, they would not produce a positive Dix-Hallpike test.

Answer 4: Meclizine is an antagonist at the histamine H1 receptor and can be used as second-line therapy for BPV. It acts by depressing vestibular stimulation, but the Epley maneuver should be attempted first.

Answer 5: Increased fluid intake would be useful in orthostatic hypotension, which, like BPV, occurs with sudden rising. Although this patient did run a race and is therefore at risk for dehydration, his symptoms are more consistent with BPV (positive Dix-Hallpike test).

Bullet Summary:
The Epley maneuver, which repositions calcium particles in the inner ear, is the first-line treatment for benign positional vertigo.

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