Review Question - QID 108709

A 16-year-old female presents to her primary care provider for fatigue. She reports feeling well until 2 weeks ago when she became unusually tired and developed a sore throat. Her mother took her temperature at home and reports that it was as high as 101.8°F (38.8°C). The patient reports that her sore throat has started to improve in the last few days but her mother continues to be concerned that her daughter is missing school. The patient endorses heavy periods, soaking 2 menstrual pads per day and lasting for 7 days. Her last menstrual period began 2 days ago. She denies sick contacts but has 2 younger siblings and her father was recently diagnosed with multiple myeloma. Her temperature is 100.4°F (38.0°C), blood pressure is 115/72 mmHg, pulse is 106/min, and respirations are 20/min. On physical exam, the patient is tired appearing with cervical lymphadenopathy and the physical exam finding seen in Figure A. Laboratory tests are performed and reveal the following:

Leukocyte count: 18,200/mm^3
Hemoglobin: 9.7 g/dL
Hematocrit: 29%
Mean corpuscular volume: 94 µm^3
Platelets: 302,000/mm^3

A peripheral smear is performed and can be seen in Figure B. Which of the following is the most appropriate treatment for this patient's condition?