Review Question - QID 108645

A 60-year-old man presents to his primary care physician with 5 months of progressive weakness, fatigue, and dry cough. He endorses shortness of breath but denies chest pain or palpitations. He also notes night sweats over the last 3 months. He also believes that he has lost around 30 pounds during that time despite making no changes to his diet or exercise routines. His past medical history is significant for gastroesophageal reflux disease, hypertension, and myocardial infarction 8 years ago. He also has a 40-pack-year smoking history, immigrated from China 25 years ago and worked in a shipyard for most of his life. His medications include antacids, hydrochlorothiazide, enalapril, aspirin, and simvastatin. His temperature is 100.7°F (38.2°C), blood pressure is 121/77 mmHg, pulse is 80/min, and respirations are 14/min. An exam shows normal heart and lung sounds but elevated jugular venous pressure. There is no hepatomegaly, ascites, or peripheral edema. A chest radiograph is shown in Figure A. Which of the following is the most likely etiology of this patient’s symptoms?