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Review Question - QID 108413

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QID 108413 (Type "108413" in App Search)
A 12-year-old boy is brought in by his parents as they are concerned about his behavior. He is constantly arguing with his parents and blatantly defying their every request. In school, he is known for being intentionally tardy and for defying his teachers. Upon further questioning of the patient you learn about some of his recent behaviors such as beginning smoking to bother his parents. You also notice that he is disrespectful towards you. You then learn that he has also gotten into weekly fights with his peers at school with no apparent cause. In addition, last week he was seen hitting one of the local neighborhood cats with a baseball bat trying to kill it. The patient lives at home with his two parents in a pre-World War II house that was recently renovated. Physical exam is unremarkable.

Laboratory values are as follows:

Na: 140 mmol/L
K: 4.5 mmol/L
Cl: 100 mmol/L
Glucose: 80 mg/dL
Ca: 10 mmol/L
Mg: 3 mEq/L
Cr: 0.8 mg/dL
BUN: 10 mg/dL
Serum lead: < .01 µg/dL
Hb: 15 g/dL
Hct: 45%
MCV: 95
Urine toxicology: negative

As the patient leaves the office you notice him stealing all of the candy from the office candy bowl. The patient seems unconcerned about his behavior overall. Which of the following statements is most likely to be true in this patient?

This patient will likely function normally despite continuing to defy authority figures

8%

2/24

This patient is suffering from antisocial personality disorder and will likely be incarcerated in adulthood

4%

1/24

Environmental exposures are likely causing this patient's behavior

0%

0/24

The patient's symptoms could progress to antisocial personality disorder

88%

21/24

Strong D2 antagonists are first-line pharmacotherapy

0%

0/24

Select Answer to see Preferred Response

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This patient is suffering from classic symptoms of conduct disorder. The patient defies authority figures, is violent, and is even seen stealing. Since he is younger than 18 years of age the diagnosis is conduct disorder, and there is a likely progression to antisocial personality disorder when he turns 18.

Conduct disorder can be thought of as equivalent to antisocial personality disorder with the exception that conduct disorder occurs before the age of 18, and antisocial personality disorder is diagnosed at the age of 18 or later. Both disorders are characterized by violation of societal norms and the basic humanity of others. Theft, dishonesty, violence, and law-breaking are very classic behaviors seen in these individuals. They do not demonstrate remorse for their behavior, and this personality disorder is most commonly associated with criminals.

This patient is aggressive and has behavior that violates the norms of society thus the first diagnosis that should jump to mind is antisocial personality disorder. Given that this patient is a child, it is important to remember that the equivalent diagnosis is conduct disorder because antisocial personality disorder can only be diagnosed after age 18. Going forward it is important to notice some of the other potential causes of this patient's symptoms. A child that lives in a pre-war house could be exposed to lead. Lead exposure could explain this child's symptoms and would be the correct answer had his blood lead level been elevated. The patient's urine toxicology was also negative ruling out other potential intoxications as the cause.

Incorrect Answers:
Answer 1: This patient will likely continue to defy authority figures though will otherwise function fine in society is characteristic of oppositional defiant disorder. Oppositional defiant disorder is characterized by behavior that is argumentative and contrary to authority figures, though these individuals do follow cultural and moral rules. This patient's criminal behavior (hurting animals, etc.) makes this answer incorrect.
Answer 2: This patient is suffering from antisocial personality disorder and will likely be incarcerated in adulthood is incorrect based only on a technicality; you cannot make the diagnosis of antisocial personality disorder until the patient is 18 years of age. Until then the diagnosis is conduct disorder. This difference is important and it is important to note the patient's age.
Answer 3: Environmental exposures (living in an old house) causing these behaviors (aggression and abnormal behavior) would be possible with lead intoxication. The most accurate test is a blood lead level, which in this case is extremely low/undetectable, suggesting that this patient has not been exposed to lead. High yield associations with lead intoxication are inhibition of ferrochelatase, increased zinc protoprophyrin, microcytic anemia, aggression, Mee's lines of the fingernails, darkening of the ginivae (black lines), hyper-dense lead lines on radiographs of bones and exposure to old buildings and paint.
Answer 5: Strong D2 antagonists such as haloperidol and fluphenazine are not the correct management of personality disorders such as antisocial personality or conduct disorder. These drugs are appropriate in psychosis, schizophrenia, acute intoxication with PCP and other psychotic disorders and episodes. Personality disorders tend to be managed with CBT.

There are many important demographic factors associated with conduct disorder. Of note, parental substance abuse, low socioeconomic status, and oppositional behavior are some of the most prominent predictive factors (1). It is important to be aware of these epidemiological factors in particular for Step exams.

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