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Review Question - QID 104613

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QID 104613 (Type "104613" in App Search)
A 31-year-old obese Caucasian female presents to the Emergency Department late in the evening for left lower quadrant pain that has progressively worsened over the last several hours. She describes the pain as sharp and shooting, coming and going. Her last bowel movement was this morning. She has also had dysuria and urgency. Her surgical history is notable for gastric bypass surgery 2 years prior and an appendectomy at age 9. She is sexually active with her boyfriend and uses condoms. Her temperature is 99.5 deg F (37.5 deg C), blood pressure is 151/83 mmHg, pulse is 86/min, respirations are 14/minute, BMI 32. On physical exam, she has left lower quadrant tenderness to palpation with pain radiating to the left groin and left flank tenderness on palpation. Her urinalysis shows 324 red blood cells/high power field. Her pregnancy test is negative. What of the following is the next best step in management?

A KUB (kidneys, ureters and bladder) plain film

23%

3/13

Intravenous pyelogram

15%

2/13

Transvaginal ultrasound

0%

0/13

Noncontrast CT scan

62%

8/13

Exploratory laparoscopy

0%

0/13

Select Answer to see Preferred Response

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The clinical presentation is most likely consistent with nephrolithiasis. The most appropriate next step is to obtain a noncontrast helical CT scan to evaluate for renal stones.

The patient above endorses symptoms commonly found with renal stones such as colic pain (depending on where the stone is located), dysuria, urgency, nausea and vomiting. Additionally, this patient has a history of gastric bypass surgery, which increases the risk of stone formation. The patient also shows hematuria without signs of infection on urinalysis. A noncontrast helical CT scan has high sensitivity and specificity for detecting all types of renal stones and can rule out other etiology for abdominal pain (Illustration A).

Portis et al. describes that noncontrast helical CT scans have high sensitivity (95-100%) and specificity (94 to 96%) in identifying all stones types. Another advantage of this imaging modality is that measuring Hounsfield density of calculi allows one to differentiate between cysteine and uric acid stones as well as subtyping calcium containing stones. In contrast, plain films sensitivity is 45-59% and specificity is 71-77%. Plain films may not detect stones that are purely uric acid or cysteine.

Asplin et al. has found that patients who have undergone modern bariatric surgery demonstrate a higher level of hyperoxaluria, which increases the risk of renal oxalate stone formation. This is likely due to the increase absorption of oxalate absorption after surgery.

Illustration A: The image depicts a non-contrast CT of the abdomen and pelvis. A calculus is seen on the left ureter.

Incorrect Answers:
Answer 1: A plain film will detect large radiopaque stones, but may miss radiolucent stones such as uric acid or smaller size stones.
Answer 2: An intravenous pyelogram has higher sensitivity and specificity for detecting stones than a plain film and can show the degree of obstruction. However, this modality has fallen out of favor due to risk of contrast reaction and radiation exposure.
Answer 3: A transvaginal ultrasound may be useful if there is suspicion for ectopic pregnancies or adnexal lesions and masses. However, the patient is not pregnant, has no signs of pelvic inflammatory disease, and the clinical presentation is more consistent with renal stones.
Answer 5: Exploratory laporoscopy is an invasive procedure and some type of imaging would be useful for guidance before subjecting the patient to unnecessary risk and complication.

ILLUSTRATIONS:
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