Review Question - QID 104215

Molluscum contagiosum presents as single or multiple round, dome-shaped papules with central umbilication. It is caused by poxvirus.

Molluscum contagiosum is generally a self-limited disorder common in children and adults. If lesions are present in the genital regions, they should be treated to prevent spread through sexual transmission. Otherwise, treatment is typically a cosmetic preference. Lesions are treated with curettage or application of liquid nitrogen. If a patient presents with new-onset multiple lesions of molluscum contagiosum, then underlying immunosuppression should be suspected (such as HIV).

Figure A shows the classic appearance of molluscum contagiosum with a round, dome-shaped papule with central umbilication.

Incorrect Answers:
Answer 1: Human herpesvirus 6 causes roseola infantum which presents initially with a very high fever that could cause febrile seizures. The fever subsequently resolves and a maculopapular rash appears.

Answer 2: Human herpesvirus 8 causes Karposi sarcoma which presents in patients with HIV with violaceous plaques. The treatment is to raise the CD4 count with anti-retroviral medications.

Answer 3: Paramyxovirus describes measles which causes a generalized, maculopapular, and erythematous skin rash in addition to a cough, conjunctivitis, Koplik spots, a high fever, and an ill-appearing child.

Answer 5: Parvovirus B19 causes erythema infectiousum, or fifth disease. The classic dermatologic finding is a "slapped cheek" appearance.

Bullet Summary:
Molluscum contagiousum is caused by poxvirus and presents with single or multiple round, dome-shaped papules with central umbilication.