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Review Question - QID 102951

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QID 102951 (Type "102951" in App Search)
A 47-year-old African-American woman presents to her primary care physician for a general checkup appointment. She works as a middle school teacher and has a 25 pack-year smoking history. She has a body mass index (BMI) of 22 kg/m^2 and is a vegetarian. Her last menstrual period was 1 week ago. Her current medications include oral contraceptive pills. Which of the following is a risk factor for osteoporosis in this patient?

Age

0%

0/5

Body mass index

0%

0/5

Estrogen therapy

0%

0/5

Race

0%

0/5

Smoking history

80%

4/5

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This patient has a significant smoking history which is a risk factor for osteoporosis.

Osteoporosis is the most common metabolic bone disease. It is characterized by loss of bone matrix/mineralization, reduced bone mass/density, and reduced thickness of cortical and trabecular bone. Causes of osteoporosis include glucocorticoid use, physical inactivity, hyperthyroidism, and calcium deficiency. Individuals at risk for osteoporosis include Caucasians, women, those with a low body mass index, smokers, and those who are postmenopausal (from decreased estrogen levels). Patients at risk for osteoporosis should be screened using a DEXA scan for central bone density (hip and lumbar spine). The treatment of osteoporosis is elimination of risk factors (such as smoking), weight bearing exercise, and calcium/vitamin D supplementation. Medical treatment for severe or refractory osteoporosis can include bisphosphonates.

Incorrect Answer:
Answer 1: Age is not a risk factor for this patient as she is not considered elderly and is premenopausal. Given her premenopausal status, smoking is a more important risk factor for her.

Answer 2: Body-mass index can be a risk factor if the patient has a low BMI (< 19 kg/m^2). A normal BMI or being overweight is not considered a risk factor.

Answer 3: Estrogen therapy is protective against osteoporosis (though this is not an indication for starting oral contraceptive pills or estrogen replacement therapy).

Answer 4: Race is a risk factor if the patient is Caucasian; however, African American race is not considered a risk factor.

Bullet Summary:
Smoking is an important modifiable risk factor for osteoporosis.

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