Snapshot A 5-year-old boy presents to the emergency room with 5 days of fevers, ranging from 102-104°F (38.9-40°C). His mother reports that he also has a bad rash that developed on day 3. On physical exam, he has bilateral conjunctivitis, an extensive morbilliform rash on his trunk with desquamation, a bright red tongue, and swollen hands and feet. Labs are remarkable for elevated C-reactive protein, white blood cell count, and erythrocyte sedimentation rate. He is immediately given intravenous immunoglobulin and aspirin and sent for an echocardiogram. Introduction Clinical definition login to view 7 more bullets Epidemiology Demographics login to view 2 more bullets Risk factors login to view 2 more bullets Etiology Pathogenesis login to view 1 more bullet Presentation Symptoms login to view 2 more bullets Physical exam login to view 11 more bullets Imaging Echocardiography login to view 3 more bullets Studies Labs login to view 6 more bullets Differential Takayasu arteritis login to view 3 more bullets Scarlet fever login to view 3 more bullets Staphylococcal scalded skin syndrome login to view 2 more bullets Diagnosis Making the diagnosis login to view 8 more bullets Treatment Management approach login to view 1 more bullet Medical login to view 21 more bullets Complications Cardiac sequelae login to view 4 more bullets Prognosis Usually self-limited and resolves with treatment 25% of patients have cardiac sequelae login to view 2 more bullets