Zinc is an essential micronutrient for humans and is extensively involved in protein, lipid, nucleic acid metabolism, and gene transcription. Its role within the human body is extensive in reproduction, immune function, and wound repair. At the microcellular level, it has a significant effect on the normal functioning of macrophages, neutrophils, natural killer cells, and complement activity. Despite being one of the most abundant trace elements in the human body, zinc cannot be stored in significant amounts and hence requires regular intake or supplementation. Zinc is found in various foods, including meat, fish, legumes, nuts, and other dietary sources, although its absorption varies by the substrate carrying it. Zinc deficiency is a major health problem worldwide, especially in developing countries, hence it is designated by the World Health Organization as a major disease contributing factor. Zinc deficiency can present with growth impairment, sexual dysfunction, inflammation, gastrointestinal symptoms, or cutaneous involvement.