Suicide is one of the most important events that health professionals must address. The clinical assessment and subsequent intervention become critical in the optimization of life, in the setting of suicidality. Remember that suicide constitutes a permanent solution to a temporary problem. This article outlines critical statistics and risks factors so clinicians can recognize the individuals requiring special intervention, identifies the major questions to ask a potentially suicidal individual, details the actual steps to ensure the patient’s safety, and concludes steps that should be addressed with the family and friends in the case of completed suicide.[1][2][3][4][5]