Snapshot A 15-year-old girl presents to her primary care physician due to lack of breast development, which is causing her emotional distress. She denies any headache, vision changes, or focal motor or sensory deficits. Physical examination is notable for a short stature and shield chest. Bone age appears to be that of a 12-year-old girl. Serum testing is remarkable for an elevated FSH and LH with decreased serum estradiol and karyotyping demonstrates 45,XO. (Turner syndrome) Introduction Overview login to view 26 more bullets Epidemiology Risk factors login to view 4 more bullets ETIOLOGY Pathogenesis login to view 11 more bullets Presentation Symptoms login to view 2 more bullets Physical exam login to view 5 more bullets Imaging Radiography login to view 4 more bullets MRI of the brain with gadolinium login to view 2 more bullets Studies Labs login to view 7 more bullets Treatment Treatment should directed at the underlying cause, for example login to view 3 more bullets Complications Lower self-esteem due to teasing in school Increased risk of fracture secondary to decreased bone mineral density Prognosis the height of boys or girls with constitutional delay of puberty may be slightly lower than their genetic potential