Snapshot A 65-year-old man with hypertension, hyperlipidemia, and diabetes presented to the emergency room for fevers, fatigue, and a productive cough over the past few days. His temperature is 102.1°F (38.9°C) and mean arterial pressure is 63 mmHg. Further evaluation demonstrates a leukocytosis, elevated procalcitonin, and a radiographic focal consolidation in his left lower lobe. He denies any temperature intolerance, weight changes, any nail and skin abnormalities, diarrhea, or constipation. He was admitted to the intensive care unit for treatment of sepsis secondary to pneumonia. On admission, labs for thyroid function were ordered and found to be abnormal. Introduction Clinical definition login to view 1 more bullet Epidemiology Demographics login to view 1 more bullet Risk factors login to view 11 more bullets ETIOLOGY Pathogenesis login to view 6 more bullets Presentation Symptoms and physical exam are variable and specific to underlying nonthyroidal illness Studies Diagnostic testing login to view 6 more bullets Differential Thyroid disease login to view 3 more bullets Central hypopituitarism login to view 2 more bullets Medication-related login to view 3 more bullets DIAGNOSIS Diagnostic criteria login to view 6 more bullets Treatment Management approach login to view 3 more bullets Complications None