Snapshot A 27-year-old woman with vitiligo presents to her primary care physician with progressive fatigue and weight loss despite a good appetite. On exam, her blood pressure is 170/110 mmHg, pulse is 110/min, diaphoretic, displays brisk reflexes, and has bilateral exophthalmos. Introduction Clinical definition login to view 1 more bullet Genetics login to view 2 more bullets Associated conditions login to view 4 more bullets Epidemiology Demographics login to view 3 more bullets ETIOLOGY Pathogenesis login to view 5 more bullets Presentation Symptoms login to view 9 more bullets Physical exam login to view 9 more bullets imaging Radioactive iodine (123I) thyroid scan login to view 2 more bullets Computed tomography (CT) scan or magnetic resonance image (MRI) of the orbits login to view 1 more bullet Studies Diagnostic testing login to view 20 more bullets Differential Multinodular toxic goiter login to view 3 more bullets Toxic thyroid adenoma login to view 2 more bullets Iatrogenic login to view 3 more bullets DIAGNOSIS Diagnostic criteria login to view 5 more bullets Treatment Medical treatment login to view 33 more bullets Surgical treatment login to view 7 more bullets Special considerations login to view 8 more bullets Complications Thyroid storm login to view 1 more bullet Pregnancy complications login to view 2 more bullets Thyroidectomy complications login to view 3 more bullets