A 24-year-old man presents to student health in order to obtain a PPD test. He recently started training to be a volunteer in a hospital and was required to get a PPD test prior to beginning work. His medical history is significant for HIV for which he takes antiretroviral therapy. He does not have any other medical history and has never undergone surgery. He drinks 3 drinks per week and smokes 1 pack per day. His temperature is 98.6°F (37°C), blood pressure is 115/72 mmHg, pulse is 72/min, respirations are 12/min, and oxygen saturation is 99% on room air. The PPD is performed demonstrating 7 mm of induration. A chest radiograph is obtained and the results are shown in Figure A. Which of the following is the most appropriate next step in management?

A 39-year-old man presents for evaluation of cough and weight loss over the past 2 months. He reports a cough productive of yellow sputum that has been worsening over the past 2 months with associated fevers, night sweats, and a 15 pound weight loss. The patient was found to have a negative PPD and treated with azithromycin in an urgent care clinic 1 month ago, but this did not improve his symptoms. He has a history significant for liver transplant for which he takes tacrolimus. Exam reveals an ill-appearing man. Ronchi are noted over the left lung fields. A chest radiograph is obtained as shown in Figure A. An acid-fast stain of the patient's sputum is performed with the results shown in Figure B. Which of the following organisms is most likely responsible for this patient's presentation?

A 28-year-old woman presents to the emergency department wit...

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