Snapshot A 45-year-old woman presents to her primary care physician for a routine visit. She reports feeling very tired over the past few months. She also reports gaining weight over the past year due to physical inactivity and poor dieting habits. She has a 4 pack-year history of smoking. On physical exam, she is overweight but otherwise without any abnormal findings. Given her risk factors, her physician recommends a screening lipid panel as well as thyroid function tests. SUMMARY Clinical definition login to view 2 more bullets Epidemiology risk factors login to view 5 more bullets Etiology Etiology login to view 9 more bullets Pathogenesis login to view 5 more bullets Associated conditions login to view 4 more bullets Presentation Symptoms login to view 1 more bullet Physical exam login to view 9 more bullets Studies Labs login to view 14 more bullets Making the diagnosis login to view 1 more bullet Differential Hypothyroidism login to view 3 more bullets Treatment Management approach login to view 10 more bullets Conservative login to view 8 more bullets Medical login to view 18 more bullets Complications Heart disease Prognosis associated with ↑ risk of cardiovascular disease