3Spine is a Medtronic spin out. Medtronic purchased three-column IP in 2004 as the foundation for a posterior TJR IP portfolio, subsequently developing the KENAI device. In 2014 the portfolio was spun out to a private shell with Medtronic’s support to complete additional refinements and the US IDE, leveraging private capital. International Surgical purchased the IP in 2016, rebranding as BalancedBack and then MOTUS. International Surgical SEZC became 3Spine SEZC then 3Spine, Inc. 3Spine is now fully capitalized and entirely independent. MOTUS is possibly the most researched biomechanical concept in spine history. Our team and prior teams at Medtronic completed primary research on spine morphology, nerve paths, movement patterns, new test methods, new materials including the first modern polyethylene13 in spine, and a first-of-kind technique. We were awarded Breakthrough Device Designation by FDA in 2020 and enjoy close collaboration with the FDA and CMS. So why the name? 3Spine is built on some basic concepts: safely cross three columns of the spine (posterior, middle, and anterior) thereby gaining access, support, and correction; thereby replacing the function of three structures (two facets and the disc); thereby dynamically balancing the three curves of the spine; thereby transitioning safely between the three sagittal activities of daily living (standing, sitting, and slumped sitting). After nearly 20 years of research and clinical use, we now have a 4th generation technology, capital, and a team who believe deeply in our mission of transforming outcomes for spine patients worldwide.

Cerapedics is a global, commercial-stage ortho-biologics company that aspires to transform the standard of care for bone repair, healing bones faster and at higher rates, without compromising safety, so that patients can live their healthiest lives. Bone grafts, including Cerapedics’ products, are used in over four million annual spine, orthopedics, trauma and interventional procedures world-wide. Cerapedics’ product, i-FACTOR®, is FDA approved for single level cervical spinal fusions in the United States. Cerapedics’ next-generation product is currently being evaluated for use in lumbar interbody fusion through ASPIRE, a pivotal IDE study, and has been granted a Breakthrough Device Designation by the FDA. Cerapedics is headquartered in Westminster, CO.

At Accelus, we believe in a procedure-centric approach, where every implant and instrument is designed to elevate the surgical experience and improve patient outcomes. Driven by a relentless pursuit of excellence, we are committed to providing spine surgeons with our cutting-edge Adaptive Geometry™ technologies for transforaminal lumbar interbody fusion (TLIF), posterior lumbar interbody fusion (PLIF), endoscopic-assisted percutaneous, and lateral spine surgeries.

ATEC is more than a medical technology company. We are an Organic Innovation Machine™ that is focused on Revolutionizing the Approach to Spine Surgery. We are committed to creating clinical distinction by developing new approaches to treat the various pathologies to ultimately achieve the goals of spine surgery. Our ultimate vision is to become The Standard-Bearer in Spine.

Decades in the making, Barricaid is the only FDA-approved device designed to close large defects in the annulus. Barricaid allows you to preserve more of your patient’s disc while reducing their risk of reherniation and reoperation. A Level I RCT (randomized controlled trial) of 554 patients showed an approximate 50% reduction in reherniation and reoperative recurrence starting at the 90-day mark and running through 36 months post-surgery.

Carlsmed’s mission is to improve outcomes and decrease the cost of healthcare for spine surgery and beyond.

Centinel Spine continues its leadership in total disc replacement—now the only company with a portfolio that allows matching the disc to meet surgeon preference and patient needs.

DePuy Synthes, the Orthopaedics Company of Johnson & Johnson, provides one of the most comprehensive Orthopaedics portfolios in the world that helps heal and restore movement for the millions of patients we serve. DePuy Synthes solutions, in specialties including joint reconstruction, trauma, craniomaxillofacial, spinal surgery and sports medicine, are designed to advance patient care while delivering clinical and economic value to health care systems worldwide. With new advancements in orthopaedic devices, medical technology, and digital surgery across the continuum of care, we are proud to provide surgeons with solutions as diverse as their patients.

Induce Biologics USA Inc. was founded to develop the next evolution of bone regeneration products. Its founders and management team have previously developed and launched several very successful orthobiologics (bone and tissue repair) products, including several bone graft substitutes. Induce Biologics is commercializing a family of bioimplants that includes Natural Matrix Protein (NMP™) which replicates the body’s native healing capabilities in order to create natural bone regeneration. The NMP™ proprietary process unlocks the growth factors naturally found in bone, making them bioavailable.

Easing the burden of spine-related pain Spine-related pain is taking a huge toll on our society: more days in bed, more days off work, and at a greater financial cost to westernized healthcare than any other condition. In fact, today, nearly 1 in 5 spinal fusion surgeries result in a non-union of the bones in the spine.

We’re passionate about developing implants and surgical approaches that are designed to make spine surgery simpler and more efficient. We have a calling to help surgeons improve patient outcomes and satisfaction. With the patented OneLIF™ interbody fusion system as our foundation, NovApproach Spine is simplifying single-position, anterior lumbar spine surgery. Uniquely supporting ALIF, SupineATP® for multi-level reconstruction, or Lateral ATP approaches, this cage offers Versatility, Simplified. Based in Alachua, Florida, just north of Gainesville and the University of Florida, the NovApproach Spine team and its board of management bring a wealth of clinical, business and operational leadership with a faith that will support the company’s fast-paced growth. Whether you’re a seasoned spine surgeon seeking cutting-edge solutions, a sales representative passionate about delivering advanced technologies, or someone interested in being part of our growth, NovApproach Spine invites you to join our transformative journey to improve spine surgery.

Providence Medical Technology, Inc. is a privately-held medical device company focused on innovative solutions for cervical spinal conditions. The company has pioneered a proprietary approach to posterior cervical fusion and has developed surgical instrumentation and implants that offer unique benefits to the $2 billion worldwide cervical spine market. Our purpose is to improve clinical outcomes for high-risk patients and prevent surgical failures of the cervical spine.

The demand for greater performance and availability in modern medical engineering is increasing worldwide. It can therefore happen that products or services are standardized across continents without taking local needs into account. Globally developed, highly complex systems often overshoot the mark from the perspective of users and buyers: they are perfect for certain applications, but often too complex or too expensive for regular use in hospital routines. In both cases, the result can be more of a compromise than an ideal solution. This can harm the business relationship between the hospital and the manufacturer – a situation which should definitely have no impact on the patient’s wellbeing. We founded Silony to reverse this situation and to counteract this trend. Silony develops and manufactures implant and instrument systems that are tailor-made to meet the requirements of the patients, physicians and hospital staff and which can be customized wherever required. We stand for commitment, integrity and team work, seek cooperation based on partnership with our customers and always welcome constructive criticism. Together, we want to – and will – make things better!

Comprehensive spinal surgery devices and solutions We help surgeons deliver better outcomes for patients. For two decades we have continued to release increasingly innovative surgical technologies, including MIS Ultra®, the newest addition to our highly differentiated suite of spinal surgery devices and technologies.

At Spineology, we are dedicated to transforming spine surgery by providing innovative, anatomy-conserving technologies for surgeons and their patients. Our proprietary mesh technology is used in the OptiMesh and Duo implants, which expand in three dimensions to create large footprints and allow placement of anatomy-conforming interbody fusion devices through very small incisions. This technology preserves spinal anatomy, increases procedural efficiency, and accelerates patient recovery.